다계통 위축증 Multiple system atrophy (MSA)

브리짓을 3일 relieving 하고 오늘부터 4일은 올리비아를 relieving 한다. 브리짓은 오늘부터 돌아왔어야했는데… 와서 아침에만 일하다 집에 갔다 집에 무슨일이 있다고 하는데 나는 무슨일인지 모른다. 아침에 기분이 안좋아보였는데 집안일인지 아니면 시험을 망친건지 둘다인지 모르겠다.  내일도 안나온다고 통보…
오늘은 레지 한명 (3명중에). 내일은 두명…에 RMO도 한명 빠지고… 아. 제발 안바쁘길


Multiple system atrophy (MSA)
-an adult-onset neurodegenerative disorder
-is rare neurodegenerative disorder that encompasses autonomic, pyramidal, parkinsonian, and cerebellar features.

It is one of several neurodegenerative disorders associated with alpha-synuclein aggregation, or synucleinopathies; others include Parkinson disease (PD) and dementia with Lewy bodies (DLB).

Clinical features
The core clinical features of MSA, which occur in varying combinations, are parkinsonism (bradykinesia plus rigidity and/or tremor), autonomic failure, cerebellar ataxia, and pyramidal signs. The onset of disease can be marked by any characteristic motor or autonomic feature

-The mean age of onset is 54 to 58 years

Parkinsonism (MSA-P) — Parkinsonism in MSA-P is characterized by akinesia/bradykinesia, rigidity, postural instability, and/or an irregular jerky postural and action tremor.

Cerebellar dysfunction (MSA-C) — In contrast to MSA-P, the motor features of MSA-C involve predominant cerebellar dysfunction that manifests as gait ataxia, limb ataxia, ataxic dysarthria, and cerebellar disturbances of eye movements